Recombinant Full Length Human KIAA0319 Protein, C-Flag-tagged

• Cat.No.: KIAA0319-1288HFL
• Product Overview: Recombinant Full Length Human KIAA0319 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 115.8 kDa
• AA Sequence: MAPPTGVLSSLLLLVTIAGCARKQC SEGRTYSNAVISPNLETTRIMRVSH TFPVVDCTAACCDLSSCDLA WWFEGRCYLVSCPHKENCEPKKMGP IRSYLTFVLRPVQRPAQLLDYGDMM LNRGSPSGIWGDSPEDIRKD LPFLGKDWGLEEMSEYADDYRELEK DLLQPSGKQEPRGSAEYTDWGLLPG SEGAFNSSVGDSPAVPAETQ QDPELHYLNESASTPAPKLPERSVL LPLPTTPSSGEVLEKEKASQLQEQS SNSSGKEVLMPSHSLPPASL ELSSVTVEKSPVLTVTPGSTEHSIP TPPTSAAPSESTPSELPISPTTAPR TVKELTVSAGDNLIITLPDN EVELKAFVAPAPPVETTYNYEWNLI SHPTDYQGEIKQGHKQTLNLSQLSV GLYVFKVTVSSENAFGEGFV NVTVKPARRVNLPPVAVVSPQLQEL TLPLTSALIDGSQSTDDTEIVSYHW EEINGPFIEEKTSVDSPVLR LSNLDPGNYSFRLTVTDSDGATNST TAALIVNNAVDYPPVANAGPNHTIT LPQNSITLNGNQSSDDHQIV LYEWSLGPGSEGKHVVMQGVQTPYL HLSAMQEGDYTFQLKVTDSSRQQST AVVTVIVQPENNRPPVAVAG PDKELIFPVESATLDGSSSSDDHGI VFYHWEHVRGPSAVEMENIDKAIAT VTGLQVGTYHFRLTVKDQQG LSSTSTLTVAVKKENNSPPRARAGG RHVLVLPNNSITLDGSRSTDDQRIV SYLWIRDGQSPAAGDVIDGS DHSVALQLTNLVEGVYTFHLRVTDS QGASDTDTATVEVQPDPRKSGLVEL TLQVGVGQLTEQRKDTLVRQ LAVLLNVLDSDIKVQKIRAHSDLST VIVFYVQSRPPFKVLKAAEVARNLH MRLSKEKADFLLFKVLRVDT AGCLLKCSGHGHCDPLTKRCICSHL WMENLIQRYIWDGESNCEWSIFYVT VLAFTLIVLTGGFTWLCICC CKRQKRTKIRKKTKYTILDNMDEQE RMELRPKYGIKHRSTEHNSSLMVSE SEFDSDQDTIFSREKMERGN
  PKVSMNGSIRNGASFSYCSKDRTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: KIAA0319 KIAA0319 [ Homo sapiens (human) ]
• Official Symbol: KIAA0319
• Synonyms: AAVR; DYX2; NMIG; DYLX2
• Gene ID: 9856
• mRNA Refseq: NM_014809.4
• Protein Refseq: NP_055624.2
• MIM: 609269
• UniProt ID: Q5VV43