Recombinant Full Length Human KRT81 Protein

• Cat.No.: KRT81-270HF
• Product Overview: Recombinant full length Human KRT81 with N terminal proprietary tag; Predicted MW 48.33 kDa

Specification

• Description: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 48.330kDa inclusive of tags
• Protein length: 202 amino acids
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: KRT81 keratin 81 [ Homo sapiens ]
• Official Symbol: KRT81
• Synonyms: KRT81; keratin 81; keratin, hair, basic, 1 , KRTHB1; keratin, type II cuticular Hb1; hard keratin type II 1; Hb 1
• Gene ID: 3887
• mRNA Refseq: NM_002281
• Protein Refseq: NP_002272
• MIM: 602153
• UniProt ID: Q14533