Recombinant Full Length Human KRT81 Protein

Cat.No. : KRT81-270HF
Product Overview : Recombinant full length Human KRT81 with N terminal proprietary tag; Predicted MW 48.33 kDa
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Description : The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Source : In Vitro Cell Free System
Species : Human
Form : Liquid
Molecular Mass : 48.330kDa inclusive of tags
Protein Length : 202 amino acids
Purity : Proprietary Purification
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer : pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.
Gene Name : KRT81 keratin 81 [ Homo sapiens ]
Official Symbol : KRT81
Synonyms : KRT81; keratin 81; keratin, hair, basic, 1 , KRTHB1; keratin, type II cuticular Hb1; hard keratin type II 1; Hb 1
Gene ID : 3887
mRNA Refseq : NM_002281
Protein Refseq : NP_002272
MIM : 602153
UniProt ID : Q14533

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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