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Recombinant Full Length Human MAP2K5 Protein, GST-tagged

Cat.No. : MAP2K5-6842HF
Product Overview : Human MAP2K5 full-length ORF ( AAH08838, 1 a.a. - 448 a.a.) recombinant protein with GST-tag at N-terminal was expressed in wheat germ.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 75.02 kDa
Protein Length : 448 amino acids
AA Sequence : MLWLALGPFPAMENQVLVIRIKIPN SGAVDWTVHSGPQLLFRDVLDVIGQ VLPEATTTAFEYEDEDGDRITVRSD EEMKAMLSYYYSTVMEQQVNGQLIE PLQIFPRACKPPGERNIHGLKVNTR AGPSQHSSPAVSDSLPSNSLKKSSA ELKKILANGQMNEQDIRYRDTLGHG NGGTVYKAYHVPSGKILAVKVILLD ITLELQKQIMSELEILYKCDSSYII GFYGAFFVENRISICTEFMDGGSLD VYRKMPEHVLGRIAVAVVKGLTYLW SLKILHRDVKPSNMLVNTRGQVKLC DFGVSTQLVNSIAKTYVGTNAYMAP ERISGEQYGIHSDVWSLGISFMELA LGRFPYPQIQKNQGSLMPLQLLQCI VDEDSPVLPVGESSEPFVHFITQCM RKQPKERPAPEELMGHPFIVQFNDG NAAVVSMWVCRALEERRSQQGPP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MAP2K5 mitogen-activated protein kinase kinase 5 [ Homo sapiens (human) ]
Official Symbol : MAP2K5
Synonyms : MAP2K5; MAPKK5; MKK5; PRKMK5; SAPKK5; SKK5; HsT17454; mitogen-activated protein kinase kinase 5; dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAPK/ERK kinase 5; MAPKK 5; MEK 5; EC 2.7.12.2
Gene ID : 5607
mRNA Refseq : NM_145160
Protein Refseq : NP_660143
MIM : 602520
UniProt ID : Q13163

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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