Recombinant Full Length Human MX1 Protein, C-Flag-tagged

• Cat.No.: MX1-646HFL
• Product Overview: Recombinant Full Length Human MX1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 75.3 kDa
• AA Sequence: MVVSEVDIAKADPAAASHPLLLNGD ATVAQKNPGSVAENNLCSQYEEKVR PCIDLIDSLRALGVEQDLAL PAIAVIGDQSSGKSSVLEALSGVAL PRGSGIVTRCPLVLKLKKLVNEDKW RGKVSYQDYEIEISDASEVE KEINKAQNAIAGEGMGISHELITLE ISSRDVPDLTLIDLPGITRVAVGNQ PADIGYKIKTLIKKYIQRQE TISLVVVPSNVDIATTEALSMAQEV DPEGDRTIGILTKPDLVDKGTEDKV VDVVRNLVFHLKKGYMIVKC RGQQEIQDQLSLSEALQREKIFFEN HPYFRDLLEEGKATVPCLAEKLTSE LITHICKSLPLLENQIKETH QRITEELQKYGVDIPEDENEKMFFL IDKINAFNQDITALMQGEETVGEED IRLFTRLRHEFHKWSTIIEN NFQEGHKILSRKIQKFENQYRGREL PGFVNYRTFETIVKQQIKALEEPAV DMLHTVTDMVRLAFTDVSIK NFEEFFNLHRTAKSKIEDIRAEQER EGEKLIRLHFQMEQIVYCQDQVYRG ALQKVREKELEEEKKKKSWD FGAFQSSSATDSSMEEIFQHLMAYH QEASKRISSHIPLIIQFFMLQTYGQ QLQKAMLQLLQDKDTYSWLL
  KERSDTSDKRKFLKERLARLTQARR RLAQFPGTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: MX1 MX dynamin like GTPase 1 [ Homo sapiens (human) ]
• Official Symbol: MX1
• Synonyms: MX; MxA; IFI78; IFI-78K; lncMX1-215
• Gene ID: 4599
• mRNA Refseq: NM_002462.5
• Protein Refseq: NP_002453.2
• MIM: 147150
• UniProt ID: P20591