Recombinant Full Length Human MX2 Protein, C-Flag-tagged

• Cat.No.: MX2-1738HFL
• Product Overview: Recombinant Full Length Human MX2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 81.9 kDa
• AA Sequence: MSKAHKPWPYRRRSQFSSRKYLKKE MNSFQQQPPPFGTVPPQMMFPPNWQ GAEKDAAFLAKDFNFLTLNN QPPPGNRSQPRAMGPENNLYSQYEQ KVRPCIDLIDSLRALGVEQDLALPA IAVIGDQSSGKSSVLEALSG VALPRGSGIVTRCPLVLKLKKQPCE AWAGRISYRNTELELQDPGQVEKEI HKAQNVMAGNGRGISHELIS LEITSPEVPDLTIIDLPGITRVAVD NQPRDIGLQIKALIKKYIQRQQTIN LVVVPCNVDIATTEALSMAH EVDPEGDRTIGILTKPDLMDRGTEK SVMNVVRNLTYPLKKGYMIVKCRGQ QEITNRLSLAEATKKEITFF QTHPYFRVLLEEGSATVPRLAERLT TELIMHIQKSLPLLEGQIRESHQKA TEELRRCGADIPSQEADKMF FLIEKIKMFNQDIEKLVEGEEVVRE NETRLYNKIREDFKNWVGILATNTQ KVKNIIHEEVEKYEKQYRGK ELLGFVNYKTFEIIVHQYIQQLVEP ALSMLQKAMEIIQQAFINVAKKHFG EFFNLNQTVQSTIEDIKVKH TAKAENMIQLQFRMEQMVFCQDQIY SVVLKKVREEIFNPLGTPSQNMKLN SHFPSNESSVSSFTEIGIHL NAYFLETSKRLANQIPFIIQYFMLR ENGDSLQKAMMQILQEKNRYSWLLQ EQSETATKRRILKERIYRLT
  QARHALCQFSSKEIHTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: MX2 MX dynamin like GTPase 2 [ Homo sapiens (human) ]
• Official Symbol: MX2
• Synonyms: MXB
• Gene ID: 4600
• mRNA Refseq: NM_002463.2
• Protein Refseq: NP_002454.1
• MIM: 147890
• UniProt ID: P20592