Recombinant Full Length Human MYOC Protein

• Cat.No.: MYOC-326HF
• Product Overview: Recombinant full length Human Myocilin with N terminal proprietary tag, 81.55 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 504 amino acids
• Description: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
• Form: Liquid
• Molecular Mass: 81.550kDa inclusive of tags
• AA Sequence: MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKA NDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSST QRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLR QENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSR EVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPY TQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPR PLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGA IVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVS SYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN PLEKKLFAWDNLNMVTYDIKLSKM
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: MYOC myocilin, trabecular meshwork inducible glucocorticoid response [ Homo sapiens ]
• Official Symbol: MYOC
• Synonyms: MYOC; myocilin, trabecular meshwork inducible glucocorticoid response; GLC1A; myocilin; JOAG1; TIGR
• Gene ID: 4653
• mRNA Refseq: NM_000261
• Protein Refseq: NP_000252
• MIM: 601652
• UniProt ID: Q99972