Recombinant Full Length Human NEFH Protein, C-Flag-tagged
Cat.No. : | NEFH-45HFL |
Product Overview : | Recombinant Full Length Human NEFH Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 111.7 kDa |
AA Sequence : | MMSFGGADALLGAPFAPLHGGGSLH YALARKGGAGGTRSAAGSSSGFHSW TRTSVSSVSASPSRFRGAGA ASSTDSLDTLSNGPEGCMVAVATSR SEKEQLQALNDRFAGYIDKVRQLEA HNRSLEGEAAALRQQQAGRS AMGELYEREVREMRGAVLRLGAARG QLRLEQEHLLEDIAHVRQRLDDEAR QREEAEAAARALARFAQEAE AARVDLQKKAQALQEECGYLRRXHQ EEVGELLGQIQGSGAAQAQMQAETR DALKCDVTSALREIRAQLEG HAVQSTLQSEEWFRVRLDRLSEAAK VNTDAMRSAQEEITEYRRQLQARTT ELEALKSTKDSLERQRSELE DRHQADIASYQEAIQQLDAELRNTK WEMAAQLREYQDLLNVKMALDIEIA AYRKLLEGEECRIGFGPIPF SLPEGLPKIPSVSTHIKVKSEEKIK VVEKSEKETVIVEEQTEETQVTEEV TEEEEKEAKEEEGKEEEGGE EEEAEGGEEETKSPPAEEAASPEKE AKSPVKEEAKSPAEAKSPEKEEAKS PAEVKSPEKAKSPAKEEAKS PPEAKSPEKEEAKSPAEVKSPEKAK SPAKEEAKSPAEAKSPEKAKSPVKE EAKSLAEAKSPVKEEAKSPA EVKSPEKAKSPTKEEAKSPEKAKSP EKEEAKSPEKAKSPVKAEAKSPEKA KSPVKAEAKSPEKAKSPVKE EAKSPEKAKSPVKEEAKSPEKAKSP VKEEAKTPEKAKSPVKEEAKSPEKA KSPEKAKTLDVKSPEAKTPA KEEARSPADKFPEKAKSPVKEEVKS PEKAKSPLKEDAKAPEKEIPKKEEV KSPVKEEEKPQEVKVKEPPK KAEEEKAPATPKTEEKKDSKKEEAP KKEAPKPKVEEKKEPAVEKPKESKV EAKKEEAEDKKKVPTPEKEA PAKVEVKEDAKPKEKTEVAKKEPDD AKAKEPSKPAEKKEAAPEKKDTKEE KAKKPEEKPKTEAKAKEDDK TLSKEPSKPKAEKAEKSSSTDQKDS KPPEKATEDKAAKGKTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Amyotrophic lateral sclerosis (ALS) |
Gene Name : | NEFH neurofilament heavy chain [ Homo sapiens (human) ] |
Official Symbol : | NEFH |
Synonyms : | NFH; CMT2CC |
Gene ID : | 4744 |
mRNA Refseq : | NM_021076.4 |
Protein Refseq : | NP_066554.2 |
MIM : | 162230 |
UniProt ID : | P12036 |
Products Types
◆ Recombinant Protein | ||
NEFH-1496H | Recombinant Human NEFH Protein, His (Fc)-Avi-tagged | +Inquiry |
Nefh-1821R | Recombinant Rat Nefh Protein, His-tagged | +Inquiry |
Nefh-4362M | Recombinant Mouse Nefh Protein, Myc/DDK-tagged | +Inquiry |
NEFH-1254H | Recombinant Human NEFH, His-tagged | +Inquiry |
NEFH-3222M | Recombinant Mouse NEFH protein, His-tagged | +Inquiry |
◆ Native Protein | ||
NEFH-181B | Native Bovine NEFH Protein | +Inquiry |
NEFH-180B | Native bovine NEFH | +Inquiry |
NEFH-01P | Native Pig NEFH Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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