Recombinant Full Length Human NKX6-1 Protein, N-GST,C-His-tagged

• Cat.No.: NKX6-1-12HFL
• Product Overview: Purified recombinant protein of Human NK6 homeobox 1 (NKX6-1), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli.

Specification

• Description: In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].
• Source: E. coli
• Species: Human
• Tag: N-GST,C-His
• Form: 50 mM Tris-HCl, pH 8.0, 8 M urea.
• Molecular Mass: 65.7 kDa
• AA Sequence: A DNA sequence encoding human full-length NKX6-1
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80 centigrade.
• Concentration: >0.05 μg/μL as determined by microplate BCA method.
• Use/Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: NKX6-1 NK6 homeobox 1 [ Homo sapiens (human) ]
• Official Symbol: NKX6-1
• Synonyms: NKX6-1; NK6 homeobox 1; NKX6A; NKX6.1
• Gene ID: 4825
• mRNA Refseq: NM_006168.3
• Protein Refseq: NP_006159.2
• MIM: 602563
• UniProt ID: P78426