| Description : |
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
75.240kDa inclusive of tags |
| Protein Length : |
451 amino acids |
| AA Sequence : |
MPHNSIRSGHGGLNQLGGAFVNGRP LPEVVRQRIVDLAHQGVRPCDISRQ LRVSHGCVSKILGRYYETGSIRPGV IGGSKPKVATPKVVEKIGDYKRQNP TMFAWEIRDRLLAEGVCDNDTVPSV SSINRIIRTKVQQPFNLPMDSCVAT KSLSPGHTLIPSSAVTPPESPQSDS LGSTYSINGLLGIAQPGSDKRKMDD SDQDSCRLSIDSQSSSSGPRKHLRT DAFSQHHLEPLECPFERQHYPEAYA SPSHTKGEQGLYPLPLLNSTLDDGK ATLTPSNTPLGRNLSTHQTYPVVAD PHSPFAIKQETPEVSSSSSTPSSLS SSAFLDLQQVGSGVPPFNAFPHAAS VYGQFTGQALLSGREMVGPTLPGYP PHIPTSGQGSYASSAIAGMVAGSEY SGNAYGHTPYSSYSEAWRFPNSSLL SSPYYYSSTSRPSAPPTTATAFDHL |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
