Recombinant Full Length Human PGM3 Protein, C-Flag-tagged

• Cat.No.: PGM3-2037HFL
• Product Overview: Recombinant Full Length Human PGM3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 59.7 kDa
• AA Sequence: MDLGAITKYSALHAKPNGLILQYGT AGFRTKAEHLDHVMFRMGLLAVLRS KQTKSTIGVMVTASHNPEED NGVKLVDPLGEMLAPSWEEHATCLA NAEEQDMQRVLIDISEKEAVNLQQD AFVVIGRDTRPSSEKLSQSV IDGVTVLGGQFHDYGLLTTPQLHYM VYCRNTGGRYGKATIEGYYQKLSKA FVELTKQASCSGDEYRSLKV DCANGIGALKLREMEHYFSQGLSVQ LFNDGSKGKLNHLCGADFVKSHQKP PQGMEIKSNERCCSFDGDAD RIVYYYHDADGHFHLIDGDKIATLI SSFLKELLVEIGESLNIGVVQTAYA NGSSTRYLEEVMKVPVYCTK TGVKHLHHKAQEFDIGVYFEANGHG TALFSTAVEMKIKQSAEQLEDKKRK AAKMLENIIDLFNQAAGDAI SDMLVIEAILALKGLTVQQWDALYT DLPNRQLKVQVADRRVISTTNAERQ AVTPPGLQEAINDLVKKYKL SRAFVRPSGTEDVVRVYAEADSQES ADHLAHEVSLAVFQLAGGIGERPQP GF TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Amino sugar and nucleotide sugar metabolism

Gene Information

• Gene Name: PGM3 phosphoglucomutase 3 [ Homo sapiens (human) ]
• Official Symbol: PGM3
• Synonyms: AGM1; PAGM; IMD23; PGM 3
• Gene ID: 5238
• mRNA Refseq: NM_015599.3
• Protein Refseq: NP_056414.1
• MIM: 172100
• UniProt ID: O95394