Recombinant Full Length Human PI3 Protein, C-Flag-tagged

• Cat.No.: PI3-1204HFL
• Product Overview: Recombinant Full Length Human PI3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 9.9 kDa
• AA Sequence: MRASSFLIVVVFLIAGTLVLEAAVT GVPVKGQDTVKGRVPFNGQDPVKGQ VSVKGQDKVKAQEPVKGPVS
  TKPGSCPIILIRCAMLNPPNRCLKD TDCPGIKKCCEGSCGMACFVPQTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane

Gene Information

• Gene Name: PI3 peptidase inhibitor 3 [ Homo sapiens (human) ]
• Official Symbol: PI3
• Synonyms: ESI; WAP3; SKALP; WFDC14; cementoin
• Gene ID: 5266
• mRNA Refseq: NM_002638.4
• Protein Refseq: NP_002629.1
• MIM: 182257
• UniProt ID: P19957