Recombinant Full Length Human PINK1 Protein, GST-tagged

• Cat.No.: PINK1-6264HF
• Product Overview: Human PINK1 full-length ORF (AAH28215.1, 1 a.a. - 581 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: Liquid
• Molecular Mass: 89.1 kDa
• Protein Length: 581 amino acids
• AA Sequence: MAVRQALGRGLQLGRALLLRFTGKP GRAYGLGRPGPAAGCVRGERPGWAA GPGAEPRRVGLGLPNRLRFFRQSVA GLAARLQRQFVVRAWGCAGPCGRAV FLAFGLGLGLIEEKQAESRRAVSAC QEIQAIFTQKSKPGPDPLDTRRLQG FRLEEYLIGQSIGKGCSAAVYEATM PTLPQNLEVTKSTGLLPGRGPGTSA PGEGQERAAGAPAFPLAIKMMWNIS AGSSSEAILNTMSQELVPASRVALA GEYGAVTYRKSKRGPKQLAPHPNII RVLRAFTSSVPLLPGALVDYPDVLP SRLHPEGLGHGRTLFLVMKNYPCTL RQYLCVNTPSPRLAAMMLLQLLEGV DHLVQQGIAHRDLKSDNILVELDPD GCPWLVIADFGCCLADESIGLQLPF SSWYVDRGGNGCLMAPEVSTARPGP RAVIDYSKADAWAVGAIAYEIFGLV NPFYGQGKAHLESRSYQEAQLPALP ESVPPDVRQLVRALLQREASKRPSA RVAANVLHLSLWGEHILALKNLKLD KMVGWLLQQSAATLLANRLTEKCCV ETKMKMLFLANLECETLCQAALLLC SWRAAL
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: PINK1 PTEN induced putative kinase 1 [ Homo sapiens ]
• Official Symbol: PINK1
• Synonyms: PINK1; PTEN induced putative kinase 1; PARK6, Parkinson disease (autosomal recessive) 6; serine/threonine-protein kinase PINK1, mitochondrial; protein kinase BRPK; PTEN-induced putative kinase protein 1; BRPK; PARK6; FLJ27236
• Gene ID: 65018
• mRNA Refseq: NM_032409
• Protein Refseq: NP_115785
• MIM: 608309
• UniProt ID: Q9BXM7