Recombinant Full Length Human PLIN1 Protein, C-Flag-tagged

• Cat.No.: PLIN1-130HFL
• Product Overview: Recombinant Full Length Human PLIN1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.8 kDa
• AA Sequence: MAVNKGLTLLDGDLPEQENVLQRVL QLPVVSGTCECFQKTYTSTKEAHPL VASVCNAYEKGVQSASSLAA WSMEPVVRRLSTQFTAANELACRGL DHLEEKIPALQYPPEKIASELKDTI STRLRSARNSISVPIASTSD KVLGAALAGCELAWGVARDTAEFAA NTRAGRLASGGADLALGSIEKVVEY LLPADKEESAPAPGHQQAQE SPKAKPSLLSRVGALTNTLSRYTVQ TMARALEQGHTVAMWIPGVVPLSSL AQWGASVAMQAVSRRRSEVR VPWLHSLAAAQEEDHEDQTDTEGED TEEEEELETEENKFSEVAALPGPRG LLGGVAHTLQKTLQTTISAV TWAPAAVLGMAGRVLHLTPAPAVSS TKGRAMSLSDALKGVTDNVVDTVVH YVPLPRLSLMEPESEFRDID NPPAEVERREAERRASGAPSAGPEP APRLAQPRRSLRSAQSPGAPPGPGL EDEVATPAAPRPGFPAVPRE
  KPKRRVSDSFFRPSVMEPILGRTHY SQLRKKSTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: PPAR signaling pathway

Gene Information

• Gene Name: PLIN1 perilipin 1 [ Homo sapiens (human) ]
• Official Symbol: PLIN1
• Synonyms: PERI; PLIN; FPLD4
• Gene ID: 5346
• mRNA Refseq: NM_002666.5
• Protein Refseq: NP_002657.3
• MIM: 170290
• UniProt ID: O60240