Recombinant Full Length Human PMP22 Protein, C-Flag-tagged
Cat.No. : | PMP22-504HFL |
Product Overview : | Recombinant Full Length Human PMP22 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 17.7 kDa |
AA Sequence : | MLLLLLSIIVLHVAVLVLLFVSTIV SQWIVGNGHATDLWQNCSTSSSGNV HHCFSSSPNEWLQSVQATMI LSIIFSILSLFLFFCQLFTLTKGGR FYITGIFQILAGLCVMSAAAIYTVR HPEWHLNSDYSYGFAYILAW VAFPLALLSGVIYVILRKRETRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Transmembrane |
Gene Name : | PMP22 peripheral myelin protein 22 [ Homo sapiens (human) ] |
Official Symbol : | PMP22 |
Synonyms : | DSS; CIDP; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA |
Gene ID : | 5376 |
mRNA Refseq : | NM_000304.4 |
Protein Refseq : | NP_000295.1 |
MIM : | 601097 |
UniProt ID : | Q01453 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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