Recombinant Full Length Human RAB5A Protein, C-Flag-tagged

• Cat.No.: RAB5A-859HFL
• Product Overview: Recombinant Full Length Human RAB5A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including amyloid-beta clearance by transcytosis; early endosome to late endosome transport; and regulation of exocytosis. Located in several cellular components, including cytoplasmic side of early endosome membrane; nucleoplasm; and terminal bouton.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 23.5 kDa
• AA Sequence: MASRGATRPNGPNTGNKICQFKLVL LGESAVGKSSLVLRFVKGQFHEFQE STIGAAFLTQTVCLDDTTVK FEIWDTAGQERYHSLAPMYYRGAQA AIVVYDITNEESFARAKNWVKELQR QASPNIVIALSGNKADLANK RAVDFQEAQSYADDNSLLFMETSAK TSMNVNEIFMAIAKKLPKNEPQNPG ANSARGRGVDLTEPTQPTRN
  QCCSNTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Endocytosis

Gene Information

• Gene Name: RAB5A RAB5A, member RAS oncogene family [ Homo sapiens (human) ]
• Official Symbol: RAB5A
• Synonyms: RAB5
• Gene ID: 5868
• mRNA Refseq: NM_004162.5
• Protein Refseq: NP_004153.2
• MIM: 179512
• UniProt ID: P20339