Recombinant Full Length Human RASGEF1A Protein, C-Flag-tagged

• Cat.No.: RASGEF1A-2193HFL
• Product Overview: Recombinant Full Length Human RASGEF1A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables guanyl-nucleotide exchange factor activity. Involved in cell migration and positive regulation of Ras protein signal transduction. Predicted to be located in cytosol.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 54.4 kDa
• AA Sequence: MPQTSVVFSSILGPSCSGQVQPGMG ERGGGAGGGSGDLIFQDGHLISGSL EALMEHLVPTVDYYPDRTYI FTFLLSSRVFMPPHDLLARVGQICV EQKQQLEAGPEKAKLKSFSAKIVQL LKEWTEAFPYDFQDEKAMAE LKAITHRVTQCDEENGTVKKAIAQM TQSLLLSLAARSQLQELREKLRPPA VDKGPILKTKPPAAQKDILG VCCDPLVLAQQLTHIELDRVSSIYP EDLMQIVSHMDSLDNHRCRGDLTKT YSLEAYDNWFNCLSMLVATE VCRVVKKKHRTRMLEFFIDVARECF NIGNFNSMMAIISGMNLSPVARLKK TWSKVKTAKFDVLEHHMDPS SNFCNYRTALQGATQRSQMANSSRE KIVIPVFNLFVKDIYFLHKIHTNHL PNGHINFKKFWEISRQIHEF MTWTQVECPFEKDKKIQSYLLTAPI YSEEALFVASFESEGPENHVEKDSW KTLRTTLLNRA TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: RASGEF1A RasGEF domain family member 1A [ Homo sapiens (human) ]
• Official Symbol: RASGEF1A
• Synonyms: CG4853
• Gene ID: 221002
• mRNA Refseq: NM_145313.4
• Protein Refseq: NP_660356.2
• MIM: 614531
• UniProt ID: Q8N9B8