Recombinant Full Length Human RASSF8 Protein, C-Flag-tagged

• Cat.No.: RASSF8-1735HFL
• Product Overview: Recombinant Full Length Human RASSF8 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 45.3 kDa
• AA Sequence: MELKVWVDGVQRIVCGVTEVTTCQE VVIALAQAIGRTGRYTLIEKWRDTE RHLAPHENPIISLNKWGQYASDVQL ILRRTGPSLSERPTSDSVARIPERT LYRQSLPPLAKLRPQIDKSIKRREP KRKSLTFTGGAKGLMDIFGKGKETE FKQKVLNNCKTTADELKKLIRLQTE KLQSIEKQLESNEIEIRFWEQKYNS NLEEEIVRLEQKIKRNDVEIEEEEF WENELQIEQENEKQLKDQLQEIRQK ITECENKLKDYLAQIRTMESGLEAE KLQREVQEAQVNEEEVKGKIGKVKG EIDIQGQQSLRLENGIKAVERSLGQ ATKRLQDKEQELEQLTKELRQVNLQ QFIQQTGTKVTVLPAEPIEIEASHA DIEREAPFQSGSLKRPGSSRQLPSN LRILQNPISSGFNPEGIYVTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: RASSF8 Ras association domain family member 8 [ Homo sapiens (human) ]
• Official Symbol: RASSF8
• Synonyms: HOJ1; C12orf2
• Gene ID: 11228
• mRNA Refseq: NM_007211.5
• Protein Refseq: NP_009142.2
• MIM: 608231
• UniProt ID: Q8NHQ8