Recombinant Human RASSF8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RASSF8-2343H
• Product Overview: RASSF8 MS Standard C13 and N15-labeled recombinant protein (NP_009142) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.4 kDa
• AA Sequence: MELKVWVDGVQRIVCGVTEVTTCQE VVIALAQAIGRTGRYTLIEKWRDTE RHLAPHENPIISLNKWGQYASDVQL ILRRTGPSLSERPTSDSVARIPERT LYRQSLPPLAKLRPQIDKSIKRREP KRKSLTFTGGAKGLMDIFGKGKETE FKQKVLNNCKTTADELKKLIRLQTE KLQSIEKQLESNEIEIRFWEQKYNS NLEEEIVRLEQKIKRNDVEIEEEEF WENELQIEQENEKQLKDQLQEIRQK ITECENKLKDYLAQIRTMESGLEAE KLQREVQEAQVNEEEVKGKIGKVKG EIDIQGQQSLRLENGIKAVERSLGQ ATKRLQDKEQELEQLTKELRQVNLQ QFIQQTGTKVTVLPAEPIEIEASHA DIERGIIILSDKQECKDTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RASSF8 Ras association domain family member 8 [ Homo sapiens (human) ]
• Official Symbol: RASSF8
• Synonyms: RASSF8; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; C12orf2, chromosome 12 open reading frame 2; ras association domain-containing protein 8; HoJ 1; carcinoma-associated protein HOJ-1; HOJ1; C12orf2; FLJ11542; DKFZp434O0227
• Gene ID: 11228
• mRNA Refseq: NM_007211
• Protein Refseq: NP_009142
• MIM: 608231
• UniProt ID: Q8NHQ8