Recombinant Full Length Human RASSF8 Protein, GST-tagged

• Cat.No.: RASSF8-2020HF
• Product Overview: Human C12orf2 full-length ORF ( AAH30021, 1 a.a. - 392 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 68.86 kDa
• Protein Length: 392 amino acids
• AA Sequence: MELKVWVDGVQRIVCGVTEVTTCQE VVIALAQAIGRTGRYTLIEKWRDTE RHLAPHENPIISLNKWGQYASDVQL ILRRTGPSLSERPTSDSVARIPERT LYRQSLPPLAKLRPQIDKSIKRREP KRKSLTFTGGAKGLMDIFGKGKETE FKQKVLNNCKTTADELKKLIRLQTE KLQSIEKQLESNEIEIRFWEQKYNS NLEEEIVRLEQKIKRNDVEIEEEEF WENELQIEQENEKQLKDQLQEIRQK ITECENKLKDYLAQIRTMESGLEAE KLQREVQEAQVNEEEVKGKIGKVKG EIDIQGQQSLRLENGIKAVERSLGQ ATKRLQDKEQELEQLTKELRQVNLQ QFIQQTGTKVTVLPAEPIEIEASHA DIERGIIILSDKQECKD
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 [ Homo sapiens ]
• Official Symbol: RASSF8
• Synonyms: RASSF8; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; C12orf2, chromosome 12 open reading frame 2; ras association domain-containing protein 8; HoJ 1; carcinoma-associated protein HOJ-1; HOJ1; C12orf2; FLJ11542; DKFZp434O0227
• Gene ID: 11228
• mRNA Refseq: NM_001164746
• Protein Refseq: NP_001158218
• MIM: 608231
• UniProt ID: Q8NHQ8