Recombinant Full Length Human RBPJ Protein, N-His-tagged

• Cat.No.: RBPJ-1960HFL
• Product Overview: Recombinant Full Length Human RBPJ Protein, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 55.5 kDa
• AA Sequence: A DNA sequence encoding human full-length RBPJ
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Protein Families: Transcription Factors
• Protein Pathways: Notch signaling pathway

Gene Information

• Gene Name: RBPJ recombination signal binding protein for immunoglobulin kappa J region [ Homo sapiens (human) ]
• Official Symbol: RBPJ
• Synonyms: SUH; csl; AOS3; CBF1; KBF2; CBF-1; RBP-J; RBPJK; IGKJRB; RBP-JK; RBPSUH; IGKJRB1; RBP-J kappa
• Gene ID: 3516
• mRNA Refseq: NM_005349.4
• Protein Refseq: NP_005340.2
• MIM: 147183
• UniProt ID: Q06330