Recombinant Full Length Human RS1 Protein, C-Flag-tagged

• Cat.No.: RS1-561HFL
• Product Overview: Recombinant Full Length Human RS1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 23 kDa
• AA Sequence: MSRKIEGFLLLLLFGYEATLGLSST EDEGEDPWYQKACKCDCQGGPNALW SAGATSLDCIPECPYHKPLG FESGEVTPDQITCSNPEQYVGWYSS WTANKARLNSQGFGCAWLSKFQDSS QWLQIDLKEIKVISGILTQG RCDIDEWMTKYSVQYRTDERLNWIY YKDQTGNNRVFYGNSDRTSTVQNLL RPPIISRFIRLIPLGWHVRI
  AIRMELLECVSKCATRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: RS1 retinoschisin 1 [ Homo sapiens (human) ]
• Official Symbol: RS1
• Synonyms: RS; XLRS1
• Gene ID: 6247
• mRNA Refseq: NM_000330.4
• Protein Refseq: NP_000321.1
• MIM: 300839
• UniProt ID: O15537