Description : |
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. |
Source : |
In Vitro Cell Free System |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
89 kDa |
Protein Length : |
555 amino acids |
AA Sequence : |
MPTTVDDVLEHGGEFHFFQKQMFFL LALLSATFAPIYVGIVFLGFTPDHR CRSPGVAELSLRCGWSPAEELNYTV PGPGPAGEASPRQCRRYEVDWNQST FDCVDPLASLDTNRSRLPLGPCRDG WVYETPGSSIVTEFNLVCANSWMLD LFQSSVNVGFFIGSMSIGYIADRFG RKLCLLTTVLINAAAGVLMAISPTY TWMLIFRLIQGLVSKAGWLIGYILI TEFVGRRYRRTVGIFYQVAYTVGLL VLAGVAYALPHWRWLQFTVALPNFF FLLYYWCIPESPRWLISQNKNAEAM RIIKHIAKKNGKSLPASLQRLRLEE ETGKKLNPSFLDLVRTPQIRKHTMI LMYNWFTSSVLYQGLIMHMGLAGDN IYLDFFYSALVEFPAAFMIILTIDR IGRRYPWAASNMVAGAACLASVFIP GDLQWLKIIISCLGRMGITMAYEIV CLVNAELYPTFIRNLGVHICSSMCD IGGIITPFLVYRLTNIWLELPLMVF GVLGLVAGGLVLLLPETKGKALPET IEEAENMQRPRKNKEKMIYLQVQKL DIPLN |
Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : |
Best use within three months from the date of receipt of this protein |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |