Recombinant Full Length Human SLC25A20 Protein, C-Flag-tagged

• Cat.No.: SLC25A20-1973HFL
• Product Overview: Recombinant Full Length Human SLC25A20 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 32.8 kDa
• AA Sequence: MADQPKPISPLKNLLAGGFGGVCLV FVGHPLDTVKVRLQTQPPSLPGQPP MYSGTFDCFRKTLFREGITG LYRGMAAPIIGVTPMFAVCFFGFGL GKKLQQKHPEDVLSYPQLFAAGMLS GVFTTGIMTPGERIKCLLQI QASSGESKYTGTLDCAKKLYQEFGI RGIYKGTVLTLMRDVPASGMYFMTY EWLKNIFTPEGKRVSELSAP RILVAGGIAGIFNWAVAIPPDVLKS RFQTAPPGKYPNGFRDVLRELIRDE GVTSLYKGFNAVMIRAFPAN AACFLGFEVAMKFLNWATPNL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: SLC25A20 solute carrier family 25 member 20 [ Homo sapiens (human) ]
• Official Symbol: SLC25A20
• Synonyms: CAC; CACT
• Gene ID: 788
• mRNA Refseq: NM_000387.6
• Protein Refseq: NP_000378.1
• MIM: 613698
• UniProt ID: O43772