Description : |
This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids, and appears to function in the reabsorption of cystine in the kidney tubule. Mutations in this gene cause non-type I cystinuria, a disease that leads to cystine stones in the urinary system due to impaired transport of cystine and dibasic amino acids. Two transcript variants, which encode the same protein, have been found for this gene. |
Source : |
In Vitro Cell Free System |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
79.9 kDa |
Protein Length : |
487 amino acids |
AA Sequence : |
MGDTGLRKRREDEKSIQSQEPKTTS LQKELGLISGISIIVGTIIGSGIFV SPKSVLSNTEAVGPCLIIWAACGVL ATLGALCFAELGTMITKSGGEYPYL MEAYGPIPAYLFSWASLIVIKPTSF AIICLSFSEYVCAPFYVGCKPPQIV VKCLAAAAILFISTVNSLSVRLGSY VQNIFTAAKLVIVAIIIISGLVLLA QGNTKNFDNSFEGAQLSVGAISLAF YNGLWAYDGWNQLNYITEELRNPYR NLPLAIIIGIPLVTACYILMNVSYF TVMTATELLQSQAVAVTFGDRVLYP ASWIVPLFVAFSTIGAANGTCFTAG RLIYVAGREGHMLKVLSYISVRRLT PAPAIIFYGIIATIYIIPGDINSLV NYFSFAAWLFYGLTILGLIVMRFTR KELERPIKVPVVIPVLMTLISVFLV LAPIISKPTWEYLYCVLFILSGLLF YFLFVHYKFGWAQKISKPITMHLQM LMEVVPPEEDPE |
Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : |
Best use within three months from the date of receipt of this protein |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |