Recombinant Full Length Human SMARCA1 Protein, C-Flag-tagged

• Cat.No.: SMARCA1-1538HFL
• Product Overview: Recombinant Full Length Human SMARCA1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 122.4 kDa
• AA Sequence: MEQDTAAVAATVAAADATATIVVIE DEQPGPSTSQEEGAAAAATEATAAT EKGEKKKEKNVSSFQLKLAA KAPKSEKEMDPEYEEKMKADRAKRF EFLLKQTELFAHFIQPSAQKSPTSP LNMKLGRPRIKKDEKQSLIS AGDYRHRRTEQEEDEELLSESRKTS NVCIRFEVSPSYVKGGPLRDYQIRG LNWLISLYENGVNGILADEM GLGKTLQTIALLGYLKHYRNIPGPH MVLVPKSTLHNWMNEFKRWVPSLRV ICFVGDKDARAAFIRDEMMP GEWDVCVTSYEMVIKEKSVFKKFHW RYLVIDEAHRIKNEKSKLSEIVREF KSTNRLLLTGTPLQNNLHEL WALLNFLLPDVFNSADDFDSWFDTK NCLGDQKLVERLHAVLKPFLLRRIK TDVEKSLPPKKEIKIYLGLS KMQREWYTKILMKDIDVLNSSGKMD KMRLLNILMQLRKCCNHPYLFDGAE PGPPYTTDEHIVSNSGKMVV LDKLLAKLKEQGSRVLIFSQMTRLL DILEDYCMWRGYEYCRLDGQTPHEE REDKFLEVEFLGQREAIEAF NAPNSSKFIFMLSTRAGGLGINLAS ADVVILYDSDWNPQVDLQAMDRAHR IGQKKPVRVFRLITDNTVEE RIVERAEIKLRLDSIVIQQGRLIDQ QSNKLAKEEMLQMIRHGATHVFASK ESELTDEDITTILERGEKKT AEMNERLQKMGESSLRNFRMDIEQS LYKFEGEDYREKQKLGMVEWIEPPK RERKANYAVDAYFREALRVS EPKIPKAPRPPKQPNVQDFQFFPPR LFELLEKEILYYRKTIGYKVPRNPD IPNPALAQREEQKKIDGAEP LTPEETEEKEKLLTQGFTNWTKRDF NQFIKANEKYGRDDIDNIAREVEGK SPEEVMEYSAVFWERCNELQ DIEKIMAQIERGEARIQRRISIKKA LDAKIARYKAPFHQLRIQYGTSKGK NYTEEEDRFLICMLHKMGFD RENVYEELRQCVRNAPQFRFDWFIK SRTAMEFQRRCNTLISLIEKENMEI EERERAEKKKRATKTPMVKF
  SAFSTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors

Gene Information

• Gene Name: SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [ Homo sapiens (human) ]
• Official Symbol: SMARCA1
• Synonyms: SWI; ISWI; SWI2; SNF2L; SNF2L1; SNF2LB; SNF2LT; hSNF2L; NURF140
• Gene ID: 6594
• mRNA Refseq: NM_003069.5
• Protein Refseq: NP_003060.2
• MIM: 300012
• UniProt ID: P28370