Recombinant Full Length Human SNAPIN Protein, C-Flag-tagged

• Cat.No.: SNAPIN-2091HFL
• Product Overview: Recombinant Full Length Human SNAPIN Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 14.7 kDa
• AA Sequence: MAGAGSAAVSGAGTPVAGPTGRDLF AEGLLEFLRPAVQQLDSHVHAVRES QVELREQIDNLATELCRINE DQKVALDLDPYVKKLLNARRRVVLV NNILQNAQERLRRLNHSVAKETARR RAMLDSGIYPPGSPGK SGPTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: SNAPIN SNAP associated protein [ Homo sapiens (human) ]
• Official Symbol: SNAPIN
• Synonyms: BLOS7; BORCS3; SNAPAP; BLOC1S7
• Gene ID: 23557
• mRNA Refseq: NM_012437.6
• Protein Refseq: NP_036569.1
• MIM: 607007
• UniProt ID: O95295