Recombinant Full Length Human SNRPA Protein, C-Flag-tagged

• Cat.No.: SNRPA-684HFL
• Product Overview: Recombinant Full Length Human SNRPA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 31.1 kDa
• AA Sequence: MAVPETRPNHTIYINNLNEKIKKDE LKKSLYAIFSQFGQILDILVSRSLK MRGQAFVIFKEVSSATNALR SMQGFPFYDKPMRIQYAKTDSDIIA KMKGTFVERDRKREKRKPKSQETPA TKKAVQGGGATPVVGAVQGP VPGMPPMTQAPRIMHHMPGQPPYMP PPGMIPPPGLAPGQIPPGAMPPQQL MPGQMPPAQPLSENPPNHIL FLTNLPEETNELMLSMLFNQFPGFK EVRLVPGRHDIAFVEFDNEVQAGAA RDALQGFKITQNNAMKISFA
  KKTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Spliceosome

Gene Information

• Gene Name: SNRPA small nuclear ribonucleoprotein polypeptide A [ Homo sapiens (human) ]
• Official Symbol: SNRPA
• Synonyms: U1A; Mud1; U1-A
• Gene ID: 6626
• mRNA Refseq: NM_004596.5
• Protein Refseq: NP_004587.1
• MIM: 182285
• UniProt ID: P09012