Recombinant Full Length Human SPINT2 Protein, C-Flag-tagged

• Cat.No.: SPINT2-2061HFL
• Product Overview: Recombinant Full Length Human SPINT2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 25.4 kDa
• AA Sequence: MAQLCGLRRSRAFLALLGSLLLSGV LAADRERSIHDFCLVSKVVGRCRAS MPRWWYNVTDGSCQLFVYGG CDGNSNNYLTKEECLKKCATVTENA TGDLATSRNAADSSVPSAPRRQDSE DHSSDMFNYEEYCTANAVTG PCRASFPRWYFDVERNSCNNFIYGG CRGNKNSYRSEEACMLRCFRQQENP PLPLGSKVVLLAGLFVMVLI LFLGASMVYLIRVARRNQERALRTV WSSGDDKEQLVKNTYVL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane

Gene Information

• Gene Name: SPINT2 serine peptidase inhibitor, Kunitz type 2 [ Homo sapiens (human) ]
• Official Symbol: SPINT2
• Synonyms: PB; Kop; HAI2; DIAR3; HAI-2
• Gene ID: 10653
• mRNA Refseq: NM_021102.4
• Protein Refseq: NP_066925.1
• MIM: 605124
• UniProt ID: O43291