Recombinant Full Length Human TNFSF18 Protein, C-Flag-tagged

• Cat.No.: TNFSF18-1491HFL
• Product Overview: Recombinant Full Length Human TNFSF18 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 22.5 kDa
• AA Sequence: MCLSHLENMPLSHSRTQGAQRSSWK LWLFCSIVMLLFLCSFSWLIFIFLQ LETAKEPCMAKFGPLPSKWQ MASSEPPCVNKVSDWKLEILQNGLY LIYGQVAPNANYNDVAPFEVRLYKN KDMIQTLTNKSKIQNVGGTY
  ELHVGDTIDLIFNSEHQVLKNNTYW GIILLANPQFISTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction

Gene Information

• Gene Name: TNFSF18 TNF superfamily member 18 [ Homo sapiens (human) ]
• Official Symbol: TNFSF18
• Synonyms: TL6; AITRL; GITRL; TNLG2A; hGITRL
• Gene ID: 8995
• mRNA Refseq: NM_005092.4
• Protein Refseq: NP_005083.3
• MIM: 603898
• UniProt ID: Q9UNG2