Recombinant Full Length Human TREM2 Protein, N-GST-tagged

• Cat.No.: TREM2-13HFL
• Product Overview: Recombinant Full Length Human TREM2 Protein, fused to GST-tag at N-terminus, was expressed in Wheat Germ (in vitro).

Specification

• Description: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Protein length: 1-222 aa
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 50.16 kDa
• AA Sequence: MEPLRLLILLFVTELSGAHNTTVFQ GVAGQSLQVSCPYDSMKHWGRRKAW CRQLGEKGPCQRVVSTHNLWLLSFL RRWNGSTAITDDTLGGTLTITLRNL QPHDAGLYQCQSLHGSEADTLRKVL VEVLADPLDHRDAGDLWFPGESESF EDAHVEHSISRPSQGSHLPSCLSKE PLGRRNPLPTHFHPSPPGLHLSHQD SSSQRPLGCSLAWTEARDTSTQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens (human) ]
• Official Symbol: TREM2
• Synonyms: TREM2; triggering receptor expressed on myeloid cells 2; PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
• Gene ID: 54209
• mRNA Refseq: NM_018965.4
• Protein Refseq: NP_061838.1
• MIM: 605086
• UniProt ID: Q9NZC2