Recombinant Full Length Human TRMT6 Protein, C-Flag-tagged

• Cat.No.: TRMT6-1634HFL
• Product Overview: Recombinant Full Length Human TRMT6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.6 kDa
• AA Sequence: MEGSGEQPGPQPQHPGDHRIRDGDF VVLKREDVFKAVQVQRRKKVTFEKQ WFYLDNVIGHSYGTAFEVTS GGSLQPKKKREEPTAETKEAGTDNR NIVDDGKSQKLTQDDIKALKDKGIK GEEIVQQLIENSTTFRDKTE FAQDKYIKKKKKKYEAIITVVKPST RILSIMYYAREPGKINHMRYDTLAQ MLTLGNIRAGNKMIVMETCA GLVLGAMMERMGGFGSIIQLYPGGG PVRAATACFGFPKSFLSGLYEFPLN KVDSLLHGTFSAKMLSSEPK DSALVEESNGTLEEKQASEQENEDS MAEAPESNHPEDQETMETISQDPEH KGPKERGSKKDYIQEKQRRQ EEQRKRHLEAAALLSERNADGLIVA SRFHPTPLLLSLLDFVAPSRPFVVY CQYKEPLLECYTKLRERGGV INLRLSETWLRNYQVLPDRSHPKLL MSGGGGYLLSGFTVAMDNLKADTSL KSNASTLESHETEEPAAKKR
  KCPESDSTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: TRMT6 tRNA methyltransferase 6 non-catalytic subunit [ Homo sapiens (human) ]
• Official Symbol: TRMT6
• Synonyms: GCD10; CGI-09; Gcd10p
• Gene ID: 51605
• mRNA Refseq: NM_015939.5
• Protein Refseq: NP_057023.2
• UniProt ID: Q9UJA5