Recombinant Full Length Human TUBB Protein, C-Flag-tagged

• Cat.No.: TUBB-100HFL
• Product Overview: Recombinant Full Length Human TUBB Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.5 kDa
• AA Sequence: MREIVHIQAGQCGNQIGAKFWEVIS DEHGIDPTGTYHGDSDLQLDRISVY YNEATGGKYVPRAILVDLEP GTMDSVRSGPFGQIFRPDNFVFGQS GAGNNWAKGHYTEGAELVDSVLDVV RKEAESCDCLQGFQLTHSLG GGTGSGMGTLLISKIREEYPDRIMN TFSVVPSPKVSDTVVEPYNATLSVH QLVENTDETYCIDNEALYDI CFRTLKLTTPTYGDLNHLVSATMSG VTTCLRFPGQLNADLRKLAVNMVPF PRLHFFMPGFAPLTSRGSQQ YRALTVPELTQQVFDAKNMMAACDP RHGRYLTVAAVFRGRMSMKEVDEQM LNVQNKNSSYFVEWIPNNVK TAVCDIPPRGLKMAVTFIGNSTAIQ ELFKRISEQFTAMFRRKAFLHWYTG EGMDEMEFTEAESNMNDLVS
  EYQQYQDATAEEEEDFGEEAEEEAT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection

Gene Information

• Gene Name: TUBB tubulin beta class I [ Homo sapiens (human) ]
• Official Symbol: TUBB
• Synonyms: M40; TUBB1; TUBB5; CDCBM6; CSCSC1; OK/SW-cl.56
• Gene ID: 203068
• mRNA Refseq: NM_178014.4
• Protein Refseq: NP_821133.1
• MIM: 191130
• UniProt ID: P07437