Recombinant Full Length Human WRAP53 Protein, C-Flag-tagged
Cat.No. : | WRAP53-1968HFL |
Product Overview : | Recombinant Full Length Human WRAP53 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 59.1 kDa |
AA Sequence : | MKTLETQPLAPDCCPSDQDPAPAHP SPHASPMNKNADSELMPPPPERGDP PRLSPDPVAGSAVSQELREG DPVSLSTPLETEFGSPSELSPRIEE QELSENTSLPAEEANGSLSEEEANG PELGSGKAMEDTSGEPAAED EGDTAWNYSFSQLPRFLSGSWSEFS TQPENFLKGCKWAPDGSCILTNSAD NILRIYNLPPELYHEGEQVE YAEMVPVLRMVEGDTIYDYCWYSLM SSAQPDTSYVASSSRENPIHIWDAF TGELRASFRAYNHLDELTAA HSLCFSPDGSQLFCGFNRTVRVFST ARPGRDCEVRATFAKKQGQSGIISC IAFSPAQPLYACGSYGRSLG LYAWDDGSPLALLGGHQGGITHLCF HPDGNRFFSGARKDAELLCWDLRQS GYPLWSLGREVTTNQRIYFD LDPTGQFLVSGSTSGAVSVWDTDGP GNDGKPEPVLSFLPQKDCTNGVSLH PSLPLLATASGQRVFPEPTE SGDEGEELGLPLLSTRHVHLECRLQ LWWCGGAPDSSIPDDHQGEKGQGGT EGGVGELI TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Gene Name : | WRAP53 WD repeat containing antisense to TP53 [ Homo sapiens (human) ] |
Official Symbol : | WRAP53 |
Synonyms : | DKCB3; TCAB1; WDR79 |
Gene ID : | 55135 |
mRNA Refseq : | NM_018081.2 |
Protein Refseq : | NP_060551.2 |
MIM : | 612661 |
UniProt ID : | Q9BUR4 |
Products Types
◆ Recombinant Protein | ||
WRAP53-5033R | Recombinant Rhesus Macaque WRAP53 Protein, His (Fc)-Avi-tagged | +Inquiry |
WRAP53-2362H | Recombinant Human WRAP53 Protein, His (Fc)-Avi-tagged | +Inquiry |
WRAP53-10204M | Recombinant Mouse WRAP53 Protein, His (Fc)-Avi-tagged | +Inquiry |
Wrap53-7008M | Recombinant Mouse Wrap53 Protein, Myc/DDK-tagged | +Inquiry |
WRAP53-6257R | Recombinant Rat WRAP53 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
WRAP53-283HCL | Recombinant Human WRAP53 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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