Recombinant Full Length Pig Membrane Cofactor Protein(Cd46) Protein, His-Tagged

• Cat.No.: RFL8067SF
• Product Overview: Recombinant Full Length Pig Membrane cofactor protein(CD46) Protein (O02839) (45-363aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Sus scrofa (Pig)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (45-363)
• AA Sequence: CDEPPKFESMRPQFLNTTYRPGDRV EYECRPGFQPMVPALPTFSVCQDDN TWSPLQEACRRKACSNLPDPLNGQV SYPNGDMLFGSKAQFTCNTGFYIIG AETVYCQVSGNVMAWSEPSPLCEKI LCKPPGEIPNGKYTNSHKDVFEYNE VVTYSCLSSTGPDEFSLVGESSLFC IGKDEWSSDPPECKVVKCPYPVVPN GEIVSGFGSKFYYKAEVVFKCNAGF TLHGRDTIVCGANSTWEPEMPQCIK DSKPTDPPATPGPSHPGPPSPSDAS PPKDAESLDGGIIAAIVVGVLAAIA VIAGGVYFFHHKYNKKRSK
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: CD46
• Synonyms: CD46; MCP; Membrane cofactor protein; CD antigen CD46
• UniProt ID: O02839

Gene Information

• Gene Name: CD46
• Synonyms: CD46; MCP; Membrane cofactor protein; CD antigen CD46
• UniProt ID: O02839

Reviews

10/19/2022

The CD46 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

08/09/2019

With the CD46 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

03/05/2019

Its unique properties make CD46 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

Q&As

How does CD46 protein interact with other immune system components?

CD46 protein interacts with complement regulatory proteins and immune cells to regulate immune responses and maintain homeostasis.

What are the potential side effects of targeting CD46 protein for therapy?

Potential side effects of targeting CD46 protein for therapy may include disturbances in immune regulation and increased susceptibility to infections.

How does the CD46 protein contribute to immune regulation?

CD46 protein regulates the activation of complement system and modulates T cell responses, contributing to immune regulation.

Can mutations in the CD46 gene lead to genetic disorders?

Mutations in the CD46 gene have been associated with genetic disorders such as atypical hemolytic uremic syndrome (aHUS) and other complement-related disorders.

Is CD46 protein involved in cancer progression or treatment resistance?

CD46 protein has been implicated in cancer progression and treatment resistance, particularly in certain types of leukemia and solid tumors.