Recombinant HIV HIVM protein, His-tagged

• Cat.No.: HIVM-173H
• Product Overview: HIV-1 gp41-gp120 is a non-glycosylated polypeptide chain fused to 6xHis Tag.

Specification

• Species: HIV
• Source: E.coli
• Tag: His
• Description: Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are charact
• Form: Sterile filtered colorless clear solution. 150mM NaCl, 25mM sodium phosphate pH-8, 50% glycerol and 150mM imidazole.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Usage: The products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
• Stability: HIV-1 gp41/120 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
• Specificity: Immunoreactive with all sera of HIV-I infected individuals.
• Shipping: Ice Packs