Recombinant Human A4GALT (Q211E) Protein, His Tagged, Mutant

• Cat.No.: A4GALT-01HM
• Product Overview: Recombinant Human A4GALT (Q211E Mutant, 44-353aa) Protein with His tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 44-353aa (Q211E)
• Description: The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene.
• Molecular Mass: 37 kDa
• AASequence: GEPKEKGQLYNLPAEIPCPTLTPPTPPSHGPTPGNIFFLETSDRTNPNFLFMCSVESAARTHPESHVLVLMKGLPGGNASLPRHLGISLLSCFPNVQMLPLDLRELFRDTPLADWYAAVQGRWEPYLLPVLSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTESRYVLNGAFLAFERRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRGVTTLPPEAFYPIPWQDWKKYFEDINPEELPRLLSATYAVHVWNKKSQGTRFEATSRALLAQLHARYCPTTHEAMKMYLGSGSGSHHHHHHHHHH
• Endotoxin: < 1 EU/μg of the protein by LAL
• Purity: >80% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile PBS, pH7.4
• Concentration: 0.44 mg/mL by BCA

Gene Information

• Gene Name: A4GALT alpha 1,4-galactosyltransferase (P1PK blood group) [ Homo sapiens (human) ]
• Official Symbol: A4GALT
• Synonyms: A4GALT; alpha 1,4-galactosyltransferase; alpha 1,4 galactosyltransferase (globotriaosylceramide synthase, P blood group); lactosylceramide 4-alpha-galactosyltransferase; A14GALT; CD77 synthase; Gb3 synthase; Gb3S; globotriaosylceramide synthase; P(k); GB3 synthase; alpha4Gal-T1; P1/Pk synthase; P(k) antigen synthase; P blood group (P one antigen); alpha-1,4-N-acetylglucosaminyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase; P1; PK; A4GALT1
• Gene ID: 53947
• mRNA Refseq: NM_017436
• Protein Refseq: NP_059132
• MIM: 607922
• UniProt ID: Q9NPC4