Recombinant Human AAAS Protein, DDK-tagged

• Cat.No.: AAAS-247H
• Product Overview: Recombinant human AAAS protein, fused to DDK tag at C-terminus, was expressed in Insect Cells.

Specification

• Description: The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
• Source: Insect cells
• Species: Human
• Tag: DDK
• Form: 50 mM Tris.HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 59.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: aladin WD repeat nucleoporin [ Homo sapiens ]
• Official Symbol: AAAS
• Synonyms: AAA; AAASb; ADRACALA; ADRACALIN; ALADIN; GL003
• Gene ID: 8086
• mRNA Refseq: NM_001173466.1
• Protein Refseq: NP_001166937.1
• MIM: 605378
• UniProt ID: 9NRG9