Recombinant Human ABCA2 protein, His-tagged
Cat.No. : | ABCA2-13H |
Product Overview : | Recombinant Human ABCA2(Leu2201~Cys2436) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 30.4kDa |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 [ Homo sapiens ] |
Official Symbol : | ABCA2 |
Synonyms : | ABCA2; ATP-binding cassette, sub-family A (ABC1), member 2; ABC2; ATP-binding cassette sub-family A member 2; ATP-binding cassette 2; ATP-binding cassette transporter 2; ATP-binding cassette, sub-family A, member 2; MGC129761; |
Gene ID : | 20 |
mRNA Refseq : | NM_001606 |
Protein Refseq : | NP_001597 |
MIM : | 600047 |
UniProt ID : | Q9BZC7 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionABCA2 is most highly expressed in the fetal and adult brain, spinal cord, ovaries and leukocytes.
It may be a lipid transporter that modulates cholesterol sequestration in late endosomes/lysosomes. ABCA2 regulates the production of amyloid-beta by modulating the activation of signaling pathways that regulate the transcription of amyloid precursor proteins by regulating sphingolipid metabolism or by its role in the γ-secretase processing of APP. And it may play a role in myelin formation.
Sure, Creative BioMart supports custom protein production services.
To improve the solubility and facilitate the subsequent experimental operation, our ABCA2 protein products use GST or His tags for your choice.
We offer a variety of expression systems, including E. coli, Yeast, Wheat Germ, and Mammalian Cell expression systems.
Creative BioMart offers recombinant ABCA2 proteins of several species, including human, mouse, and rat.
We will ensure the safety of the products on the road by putting them in ice bags or additional packaging outside the package according to the characteristics of the products.
Discounts are available for first-time purchases and for holidays. For specific promotions, please contact our customer service staff. Thank you for your inquiry and we look forward to your order.
ABCA2 is enriched in brain tissue and may play a role in neural development.
ATP binding cassette subfamily A member 2, and this protein is a member of the superfamily of ATP-binding cassette (ABC) transporters.
Customer Reviews (3)
Write a reviewI purchased the Abca2 recombinant protein and the quality is excellent, saving me weeks of research time.
Customer service representatives have provided valuable assistance in helping to decide which products best meet our research needs.
Creative BioMart's customer service is excellent, friendly and efficient, making it a worthwhile long-term partner.
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