Recombinant Human ABCG1 Protein, GST-Tagged

• Cat.No.: ABCG1-063H
• Product Overview: Human ABCG1 full-length ORF ( NP_004906.3, 1 a.a. - 678 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 102 kDa
• AA Sequence: MACLMAAFSVGTAMNASSYSAEMTE PKSVCVSVDEVVSSNMEATETDLLN GHLKKVDNNLTEAQRFSSLPRRAAV NIEFRDLSYSVPEGPWWRKKGYKTL LKGISGKFNSGELVAIMGPSGAGKS TLMNILAGYRETGMKGAVLINGLPR DLRCFRKVSCYIMQDDMLLPHLTVQ EAMMVSAHLKLQEKDEGRREMVKEI LTALGLLSCANTRTGSLSGGQRKRL AIALELVNNPPVMFFDEPTSGLDSA SCFQVVSLMKGLAQGGRSIICTIHQ PSAKLFELFDQLYVLSQGQCVYRGK VCNLVPYLRDLGLNCPTYHNPADFV MEVASGEYGDQNSRLVRAVREGMCD SDHKRDLGGDAEVNPFLWHRPSEEV KQTKRLKGLRKDSSSMEGCHSFSAS CLTQFCILFKRTFLSIMRDSVLTHL RITSHIGIGLLIGLLYLGIGNEAKK VLSNSGFLFFSMLFLMFAALMPTVL TFPLEMGVFLREHLNYWYSLKAYYL AKTMADVPFQIMFPVAYCSIVYWMT SQPSDAVRFVLFAALGTMTSLVAQS LGLLIGAASTSLQVATFVGPVTAIP VLLFSGFFVSFDTIPTYLQWMSYIS YVRYGFEGVILSIYGLDREDLHCDI DETCHFQKSEAILRELDVENAKLYL DFIVLGIFFISLRLIAYFVLRYKIR AER
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 [ Homo sapiens ]
• Official Symbol: ABCG1
• Synonyms: ABCG1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette sub-family G member 1; ABC8; ATP binding cassette transporter 8; ABC transporter 8; homolog of Drosophila white; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; white protein homolog (ATP-binding cassette transporter 8); WHITE1; MGC34313
• Gene ID: 9619
• mRNA Refseq: NM_004915
• Protein Refseq: NP_004906
• MIM: 603076
• UniProt ID: P45844