Recombinant Human ABHD12 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ABHD12-1214H |
Product Overview : | ABHD12 MS Standard C13 and N15-labeled recombinant protein (NP_001035937) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 44.9 kDa |
AA Sequence : | MRKRTEPVALEHERCAAAGSSSSGS AAAALDADCRLKQNLRLTGPAAAEP RCAADAGMKRALGRRKGVWLRLRKI LFCVLGLYIAIPFLIKLCPGIQAKL IFLNFVRVPYFIDLKKPQDQGLNHT CNYYLQPEEDVTIGVWHTVPAVWWK NAQGKDQMWYEDALASSHPIILYLH GNAGTRGGDHRVELYKVLSSLGYHV VTFDYRGWGDSVGTPSERGMTYDAL HVFDWIKARSGDNPVYIWGHSLGTG VATNLVRRLCERETPPDALILESPF TNIREEAKSHPFSVIYRYFPGFDWF FLDPITSSGIKFANDENVKHISCPL LILHAEDDPVVPFQLGRKLYSIAAP ARSFRDFKVQFVPFHSDLGYRHKYI YKSPELPRILREFLGKSEPEHQHTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ABHD12 abhydrolase domain containing 12 [ Homo sapiens (human) ] |
Official Symbol : | ABHD12 |
Synonyms : | ABHD12; abhydrolase domain containing 12; C20orf22, chromosome 20 open reading frame 22; monoacylglycerol lipase ABHD12; ABHD12A; BEM46L2; dJ965G21.2; DKFZP434P106; 2-arachidonoylglycerol hydrolase; abhydrolase domain-containing protein 12; PHARC; C20orf22; DKFZp434P106; |
Gene ID : | 26090 |
mRNA Refseq : | NM_001042472 |
Protein Refseq : | NP_001035937 |
MIM : | 613599 |
UniProt ID : | Q8N2K0 |
Products Types
◆ Recombinant Protein | ||
ABHD12-212M | Recombinant Mouse ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-12C | Recombinant Cynomolgus Monkey ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-73R | Recombinant Rat ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-247H | Recombinant Human ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABHD12-15R | Recombinant Rhesus Macaque ABHD12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ABHD12-9HCL | Recombinant Human ABHD12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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