| Description : |
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
97.4 kDa |
| AA Sequence : |
MEPLSHRGLPRLSWIDTLYSNFSYG TDEYDGEGNEEQKGPPEGSETMPYI DESPTMSPQLSARSQGGGDGVSPTP PEGLAPGVEAGKGLEMRKLVLSGFL ASEEIYINQLEALLLPMKPLKATAT TSQPVLTIQQIETIFYKIQDIYEIH KEFYDNLCPKVQQWDSQVTMGHLFQ KLASQLGVYKAFVDNYKVALETAEK CSQSNNQFQKISEELKVKGPKDSKD SHTSVTMEALLYKPIDRVTRSTLVL HDLLKHTPVDHPDYPLLQDALRISQ NFLSSINEDIDPRRTAVTTPKGETR QLVKDGFLVEVSESSRKLRHVFLFT DVLLCAKLKKTSAGKHQQYDCKWYI PLADLVFPSPEESEASPQVHPFPDH ELEDMKMKISALKSEIQKEKANKGQ SRAIERLKKKMFENEFLLLLNSPTI PFRIHNRNGKSYLFLLSSDYERSEW REAIQKLQKKDLQAFVLSSVELQVL TGSCFKLRTVHNIPVTSNKDDDESP GLYGFLHVIVHSAKGFKQSANLYCT LEVDSFGYFVSKAKTRVFRDTAEPK WDEEFEIELEGSQSLRILCYEKCYD KTKVNKDNNEIVDKIMGKGQIQLDP QTVETKNWHTDVIEMNGIKVEFSMK FTSRDMSLKRTPSKKQTGVFGVKIS VVTKRERSKVPYIVRQCVEEVEKRG IEEVGIYRISGVATDIQALKAVFDA NNKDILLMLSDMDINAIAGTLKLYF RELPEPLLTDRLYPAFMEGIALSDP AAKENCMMHLLRSLPDPNLITFLFL LEHLKRVAEKEPINKMSLHNLATVF GPTLLRPSEVESKAHLTSAADIWSH DVMAQVQVLLYYLQHPPISFAELKR NTLYFSTDVTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
