Recombinant Human ACADM Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ACADM-1433H
• Product Overview: ACADM MS Standard C13 and N15-labeled recombinant protein (NP_000007) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.6 kDa
• AA Sequence: MAAGFGRCCRVLRSISRFHWRSQHT KANRQREPGLGFSFEFTEQQKEFQA TARKFAREEIIPVAAEYDKTGEYPV PLIRRAWELGLMNTHIPENCGGLGL GTFDACLISEELAYGCTGVQTAIEG NSLGQMPIIIAGNDQQKKKYLGRMT EEPLMCAYCVTEPGAGSDVAGIKTK AEKKGDEYIINGQKMWITNGGKANW YFLLARSDPDPKAPANKAFTGFIVE ADTPGIQIGRKELNMGQRCSDTRGI VFEDVKVPKENVLIGDGAGFKVAMG AFDKTRPVVAAGAVGLAQRALDEAT KYALERKTFGKLLVEHQAISFMLAE MAMKVELARMSYQRAAWEVDSGRRN TYYASIAKAFAGDIANQLATDAVQI LGGNGFNTEYPVEKLMRDAKIYQIY EGTSQIQRLIVAREHIDKYKNTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ACADM acyl-CoA dehydrogenase medium chain [ Homo sapiens (human) ]
• Official Symbol: ACADM
• Synonyms: ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl Coenzyme A dehydrogenase, C 4 to C 12 straight chain; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD1; MCAD; MCADH; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
• Gene ID: 34
• mRNA Refseq: NM_000016
• Protein Refseq: NP_000007
• MIM: 607008
• UniProt ID: P11310