Recombinant Human ACKR4 Protein, GST-Tagged

• Cat.No.: ACKR4-0703H
• Product Overview: Human ACKR4 full-length ORF (NP_057641.1, 1 a.a. - 350 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.3 kDa
• AA Sequence: MALEQNQSTDYYYEENEMNGTYDYS QYELICIKEDVREFAKVFLPVFLTI VFVIGLAGNSMVVAIYAYYKKQRTK TDVYILNLAVADLLLLFTLPFWAVN AVHGWVLGKIMCKITSALYTLNFVS GMQFLACISIDRYVAVTKVPSQSGV GKPCWIICFCVWMAAILLSIPQLVF YTVNDNARCIPIFPRYLGTSMKALI QMLEICIGFVVPFLIMGVCYFITAR TLMKMPNIKISRPLKVLLTVVIVFI VTQLPYNIVKFCRAIDIIYSLITSC NMSKRMDIAIQVTESIALFHSCLNP ILYVFMGASFKNYVMKVAKKYGSWR RQRQSVEEFPFDSEGPTEPTSTFSI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACKR4 atypical chemokine receptor 4 [ Homo sapiens (human) ]
• Official Symbol: ACKR4
• Synonyms: ACKR4; atypical chemokine receptor 4; CCRL1; chemokine (C-C motif) receptor-like 1; C-C chemokine receptor type 11; CCBP2; CCR11; CCX CKR; PPR1; VSHK1; C-C CKR-11; CC chemokine receptor-like 1; chemocentryx chemokine receptor; chemokine, cc motif, receptor-like protein 1; orphan seven-transmembrane receptor, chemokine related; CCR10; CCR-11; CKR-11; CCX-CKR; CC-CKR-11
• Gene ID: 51554
• mRNA Refseq: NM_016557
• Protein Refseq: NP_057641
• MIM: 606065
• UniProt ID: Q9NPB9