| Description : |
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
85.43 kDa |
| AA Sequence : |
MAPYSLLVTRLQKALGVRQYHVASV LCQRAKVAMSHFEPNEYIHYDLLEK NINIVRKRLNRPLTLSEKIVYGHLD DPASQEIERGKSYLRLRPDRVAMQD ATAQMAMLQFISSGLSKVAVPSTIH CDHLIEAQVGGEKDLRRAKDINQEV YNFLATAGAKYGVGFWKPGSGIIHQ IILENYAYPGVLLIGTDSHTPNGGG LGGICIGVGGADAVDVMAGIPWELK CPKVIGVKLTGSLSGWSSPKDVILK VAGILTVKGGTGAIVEYHGPGVDSI SCTGMATICNMGAEIGATTSVFPYN HRMKKYLSKTGREDIANLADEFKDH LVPDPGCHYDQLIEINLSELKPHIN GPFTPDLAHPVAEVGKVAEKEGWPL DIRVGLIGSCTNSSYEDMGRSAAVA KQALAHGLKCKSQFTITPGSEQIRA TIERDGYAQILRDLGGIVLANACGP CIGQWDRKDIKKGEKNTIVTSYNRN FTGRNDANPETHAFVTSPEIVTALA IAGTLKFNPETDYLTGTDGKKFRLE APDADELPKGEFDPGQDTYQHPPKD SSGQHVDVSPTSQRLQLLEPFDKWD GKDLEDLQILIKVKGKCTTDHISAA GPWLKFRGHLDNISNNLLIGAINIE NGKANSVRNAVTQEFGPVPDTARYY KKHGIRWVVIGDENYGEGSSREHAA LEPRHLGGRAIITKSFARIHETNLK KQGLLPLTFADPADYNKIHPVDKLT IQGLKDFTPGKPLKCIIKHPNGTQE TILLNHTFNETQIEWFRAGSALNRM KELQQTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
