| Description : |
The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
44.45 kDa |
| AA Sequence : |
MAGKRXXGWSRAALLQLLLGVNLVV MPPTRARSLRFVTLLYRHGDRSPVK TYPKDPYQEEEWPQGFGQLTKEGML QHWELGQALRQRYHGFLNTSYHRQE VYVRSTDFDRTLMSAEANLAGLFPP NGMQRFNPNISWQPIPVHTVPITED RLLKFPLGPCPRYEQLQNETRQTPE YQNESSRNAQFLDMVANETGLTDLT LETVWNVYDTLFCEQTHGLRLPPWA SPQTMQRLSRLKDFSFRFLFGIYQQ AEKARLQGGVLLAQIRKNLTLMATT SQLPKLLVYSAHDTTLVALQMALDV YNGEQAPYASCHIFELYQEDSGNFS VEMYFRNESDKAPWPLSLPGCPHRC PLQDFLRLTEPVVPKDWQQECQLAS GPADTEVIVALAVCGSILFLLIVLL LTVLFRMQAQPPGYRHVADGEDHAT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
