Recombinant Human ACTN4 protein, GST-tagged

• Cat.No.: ACTN4-554H
• Product Overview: Recombinant Human ACTN4(1 a.a. - 911 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 131.3 kDa
• Protein length: 1 a.a. - 911 a.a.
• AA Sequence: MVDYHAANQSYQYGPSSAGNGAGGG GSMGDYMAQEDDWDRDLLLDPAWEK QQRKTFTAWCNSHLRKAGTQIENID EDFRDGLKLMLLLEVISGERLPKPE RGKMRVHKINNVNKALDFIASKGVK LVSIGAEEIVDGNAKMTLGMIWTII LRFAIQDISVEETSAKEGLLLWCQR KTAPYKNVNVQNFHISWKDGLAFNA LIHRHRPELIEYDKLRKDDPVTNLN NAFEVAEKYLDIPKMLDAEDIVNTA RPDEKAIMTYVSSFYHAFSGAQKAE TAANRICKVLAVNQENEHLMEDYEK LASDLLEWIRRTIPWLEDRVPQKTI QEMQQKLEDFRDYRRVHKPPKVQEK CQLEINFNTLQTKLRLSNRPAFMPS EGKMVSDINNGWQHLEQAEKGYEEW LLNEIRRLERLDHLAEKFRQKASIH EAWTDGKEAMLKHRDYETATLSDIK ALIRKHEAFESDLAAHQDRVEQIAA IAQELNELDYYDSHNVNTRCQKICD QWDALGSLTHSRREALEKTEKQLEA IDQLHLEYAKRAAPFNNWMESAMED LQDMFIVHTIEEIEGLISAHDQFKS TLPDADREREAILAIHKEAQRIAES NHIKLSGSNPYTTVTPQIINSKWEK VQQLVPKRDHALLEEQSKQQSNEHL RRQFASQANVVGPWIQTKMEEIGRI SIEMNGTLEDQLSHLKQYERSIVDY KPNLDLLEQQHQLIQEALIFDNKHT NYTMEHIRVGWEQLLTTIARTINEV ENQILTRDAKGISQEQMQEFRASFN HFDKDHGGALGPEEFKACLISLGYD VENDRQGEAEFNRIMSLVDPNHSGL VTFQAFIDFMSRETTDTDTADQVIA SFKVLAGDKNFITAEELRRELPPDQ AEYCIARMAPYQGPDAVPGALDYKS FSTALYGESDL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: ACTN4 actinin, alpha 4 [ Homo sapiens ]
• Official Symbol: ACTN4
• Synonyms: ACTN4; actinin, alpha 4; focal segmental glomerulosclerosis 1 , FSGS1; alpha-actinin-4; actinin alpha4 isoform; non-muscle alpha-actinin 4; F-actin cross-linking protein; focal segmental glomerulosclerosis 1; FSGS; FSGS1; ACTININ-4; DKFZp686K23158
• Gene ID: 81
• mRNA Refseq: NM_004924
• Protein Refseq: NP_004915
• MIM: 604638
• UniProt ID: O43707
• Chromosome Location: 19q13
• Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell-Cell communication, organism-specific biosystem
• Function: actin binding; actin filament binding; calcium ion binding; integrin binding; nucleoside binding; protein N-terminus binding; protein binding; protein homodimerization activity