Active Recombinant Human ACVR1 Protein, His-tagged

• Cat.No.: ACVR1-199H
• Product Overview: Recombinant extracellular domain (Met 1-Val 124) of human ALK2 (Q04771) (Met 1-Val 124) was fused with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 1-124 a.a.
• Predicted N Terminal: Met 21
• Form: Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly.
• Bio-activity: Kinase activity untested
• Molecular Mass: The secreted recombinant human ALK2 consists of 114 amino acids and has a calculated molecular mass of 12.8KDa. It migrates as an approximately 17 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >93 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: ACVR1 activin A receptor type I [ Homo sapiens ]
• Official Symbol: ACVR1
• Synonyms: FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2; TGF-B superfamily receptor type I; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor type I; activin receptor-like kinase 2; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor R1
• Gene ID: 90
• mRNA Refseq: NM_001105
• Protein Refseq: NP_001096
• MIM: 102576
• UniProt ID: Q04771
• Chromosome Location: 2q23-q24
• Pathway: ALK1 pathway, organism-specific biosystem; BMP signaling, organism-specific biosystem; Signaling pathways regulating pluripotency of stem cells, conserved biosystem