Recombinant Human ACVR1 Protein, His-tagged

Cat.No.: ACVR1-199H
Product Overview: Recombinant extracellular domain (Met 1-Val 124) of human ALK2 (Q04771) (Met 1-Val 124) was fused with a polyhistidine tag at the C-terminus.
Source: Baculovirus-Insect Cells
Species: Human
Tag: His
Predicted N Terminal: Met 21
Form: Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly.
Bio-activity: Kinase activity untested
Molecular Mass: The secreted recombinant human ALK2 consists of 114 amino acids and has a calculated molecular mass of 12.8KDa. It migrates as an approximately 17 kDa band in SDS-PAGE under reducing conditions.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: >93 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name: ACVR1 activin A receptor type I [ Homo sapiens ]
Official Symbol: ACVR1
Synonyms: FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2; TGF-B superfamily receptor type I; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor type I; activin receptor-like kinase 2; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor R1
Gene ID: 90
mRNA Refseq: NM_001105
Protein Refseq: NP_001096
MIM: 102576
UniProt ID: Q04771
Chromosome Location: 2q23-q24
Pathway: ALK1 pathway, organism-specific biosystem; BMP signaling, organism-specific biosystem; Signaling pathways regulating pluripotency of stem cells, conserved biosystem

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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