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Recombinant Human ADAM22 protein, His & T7-tagged

Cat.No. : ADAM22-1750H
Product Overview : Recombinant Human ADAM22 aa. (Leu370~Asn582 (Accession # Q9P0K1)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 27.0kDa
Protein length : Leu370~Asn582 (Accession # Q9P0K1)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 5.3
Gene Name : ADAM22 ADAM metallopeptidase domain 22 [ Homo sapiens (human) ]
Official Symbol : ADAM22
Synonyms : ADAM22; ADAM metallopeptidase domain 22; MDC2; ADAM 22; disintegrin and metalloproteinase domain-containing protein 22; a disintegrin and metalloproteinase domain 22; metalloproteinase-disintegrin ADAM22-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2
Gene ID : 53616
mRNA Refseq : NM_004194.4
Protein Refseq : NP_004185.1
UniProt ID : Q9P0K1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Where is ADAM22 mainly expressed? 08/16/2022

ADAM22 is widely expressed in the brain.

What is the function of the ADAM22? 04/07/2022

ADAM22 is a potential cell adhesion molecule.

What is the relationship between ADAM22 and protein 14-3-3β? 03/30/2021

ADAM22 interacts with protein 14-3-3β.

Which proteins have the highest homology to ADAM22? 03/14/2021

ADAM11 and ADAM23 have the highest homology to ADAM22.

In which diseases is ADAM22 primarily used in research? 01/14/2021

ADAM22 is currently being used in studies of diseases such as breast and stomach cancer.

Customer Reviews (3)

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Reviews
11/10/2022

    The company provides one-stop service, from the purchase of products to the completion of experiments in one go.

    03/01/2021

      The purity of the proteins supplied by your company was very high and satisfactory results were obtained.

      12/20/2020

        The company provided detailed information about the ADAM22 protein, which made my experiment go smoothly!

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