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Active Recombinant Human ADAMTS1 Protein, His-tagged

Cat.No. : ADAMTS1-295H
Product Overview : Human ADAMTS1 (253 a.a. - 617 a.a.) amino acids 618-968 deleted partial recombinant protein with His tag expressed in insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]
Source : Insect Cell
Species : Human
Tag : His
Form : Liquid
Bio-activity : >= 1.4 mU/mg
Molecular Mass : 41 kDa
AA Sequence : FVSSHRYVETMLVADQSMAEFHGSG LKHYLLTLFSVAARLYKHPSIRNSV SLVVVKILVIHDEQKGPEVTSNAAL TLRNFCNWQKQHNPPSDRDAEHYDT AILFTRQDLCGSQTCDTLGMADVGT VCDPSRSCSVIEDDGLQAAFTTAHE LGHVFNMPHDDAKQCASLNGVNQDS HMMASMLSNLDHSQPWSPCSAYMIT SFLDNGHGECLMDKPHNPIQLPGDL PGTSYDANRQCQFTFGEDSKHCPDA ASTCSTLWCTGTSGGVLVCQTKHFP WADGTSCGEGKWCINGKCVNKTDRK HFDTPFHGNWGMWGPWGDCSRTCGG GVQYTMRECDNPVPKNGGKYCEGKR VRYRSCNLEDCPDN
Purity : > 90% by SDS-PAGE
Applications : Functional Study
SDS-PAGE
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration : 0.2 mg/mL
Storage Buffer : In 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, pH 7.5 (0.05 % Brij-35 detergent)
Gene Name : ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 [ Homo sapiens ]
Official Symbol : ADAMTS1
Synonyms : ADAMTS1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; A disintegrin and metalloproteinase with thrombospondin motifs 1; C3 C5; KIAA1346; METH1; METH-1; ADAM-TS1; ADAMTS-1; ADAM-TS 1; human metalloproteinase with thrombospondin type 1 motifs; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; C3-C5;
Gene ID : 9510
mRNA Refseq : NM_006988
Protein Refseq : NP_008919
MIM : 605174
UniProt ID : Q9UHI8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (11)

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What is the structure domain of ADAMTS1? 11/10/2022

Pro-peptide, metallo proteinase, depolymerase/cysteine enriched region, spacer region and thrombospondin type I repeat.

My customization requirements are not listed on the page, can it be customized? 08/10/2022

Yes, you can first communicate with our experts for customized requirements.

Is it also possible to shorten the lead time for custom-manufactured proteins? 03/11/2022

The delivery cycle of this kind of protein is related to your specific customization requirements, you can communicate with our experts first.

Do you offer ADAMTS1 protein fused with other tags? 12/14/2021

We can provide ADAMTS1 protein fused with other tags.

Is ADAMTS1 widely used in disease research? 10/16/2021

ADAMTS1 applied to a variety of diseases including colon, oesophageal and lung cancers.

What physiological and pathological processes is ADAMTS1 involved in? 03/06/2021

ADAMTS1 is involved in the physiological and pathological processes of human growth and development, the formation of the urinary and reproductive systems, and the development of tumours in tissues and organs.

What are the consequences of ADAMTS1 inactivation? 01/07/2021

Inactivation of ADAMTS1 causes infertility and developmental delay in females.

Is there a discount for all ADAMTS1 proteins? 12/12/2020

Yes, all ADAMTS1 proteins are currently discounted.

What proteins does ADAMTS1 degrade? 10/26/2020

ADAMTS1 degrades extracellular matrix proteins such as versican , aggrecan , syndecan and nidogen.

I saw that proteins can be customized, can I customize ADAMTS1 for specific bands? 07/15/2019

Yes, our team can customize the protein according to your requirements.

What is the effect of adding trehalose on the preservation of protein? 06/08/2019

Trehalose can prevent protein secondary structure changes, elongation and aggregation during freeze-drying.

Customer Reviews (3)

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Reviews
03/01/2021

    Excellent after-sales service, solving many experimental problems.

    06/30/2020

      The products provided by your company are inexpensive and of high quality, and because of this, my experiments could be completed successfully.

      09/03/2019

        The price of the product is right and the quality meets my research needs.

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