| Description : |
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
80.8 kDa |
| AA Sequence : |
MNGDSRAAVVTSPPPTTAPHKERYF DRVDENNPEYLRERNMAPDLRQDFN MMEQKKRVSMILQSPAFCEELESMI QEQFKKGKNPTGLLALQQIADFMTT NVPNVYPAAPQGGMAALNMSLGMVT PVNDLRGSDSIAYDKGEKLLRCKLA AFYRLADLFGWSQLIYNHITTRVNS EQEHFLIVPFGLLYSEVTASSLVKI NLQGDIVDRGSTNLGVNQAGFTLHS AIYAARPDVKCVVHIHTPAGAAVSA MKCGLLPISPEALSLGEVAYHDYHG ILVDEEEKVLIQKNLGPKSKVLILR NHGLVSVGESVEEAFYYIHNLVVAC EIQVRTLASAGGPDNLVLLNPEKYK AKSRSPGSPVGEGTGSPPKWQIGEQ EFEALMRMLDNLGYRTGYPYRYPAL REKSKKYSDVEVPASVTGYSFASDG DSGTCSPLRHSFQKQQREKTRWLNS GRGDEASEEGQNGSSPKSKTKWTKE DGHRTSTSAVPNLFVPLNTNPKEVQ EMRNKIREQNLQDIKTAGPQSQVLC GVVMDRSLVQGELVTASKAIIEKEY QPHVIVSTTGPNPFTTLTDRELEEY RREVERKQKGSEENLDEAREQKEKS PPDQPAVPHPPPSTPIKLEEDLVPE PTTGDDSDAATFKPTLPDLSPDEPS EALGFPMLEKEEEAHRPPSPTEAPT EASPEPAPDPAPVAEEAAPSAVEEG AAADPGSDGSPGKSPSKKKKKFRTP SFLKKSKKKSDSTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
